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020-3107 8154

RAD51 Rabbit Monoclonal antibody

BRCC5, HRAD51, HsRad51, HsT16930, RAD51 homolog A

  • 货号:
    RM20268
  • 规格:
    20ul
    50ul
    100ul
    150ul
  • 价格:
    ¥0.00

产品参数

产品类型Monoclonal
基因名称RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
经测试应用WB, IP
宿主Rabbit
种属反应性Human, Mouse, Rat
免疫原A synthesized peptide derived from human RAD51
理论分子量37 kDa
实际分子量37 kDa
Gene ID(NCBI)5888
GeneBank Accession NumberBC001459
UNIPROTQ06609
形式Liquid
保存条件Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例WB:1:2500-1:25000
背景信息The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.
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