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Alix Rabbit Monoclonal antibody

Alix Rabbit Monoclonal antibody

PDCD6IP, AIP1, ALG-2-interacting protein 1, ALG-2-interacting protein X, DRIP4

货号：
RM20259
规格：

20ul

50ul

100ul

150ul
价格：
￥0.00

产品说明书

产品参数

产品类型	Monoclonal
基因名称	programmed cell death 6 interacting protein
经测试应用	WB, IHC, IF/ICC
宿主	Rabbit
种属反应性	Human, Mouse, Rat
免疫原	A synthesized peptide derived from human Alix
理论分子量	96 kDa
实际分子量	80-100 kDa
Gene ID(NCBI)	10015
GeneBank Accession Number	BC020066
UNIPROT	Q8WUM4
形式	Liquid
保存条件	Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例	WB：1:2500-1:25000
背景信息	This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15.

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