5N3, cAMP-dependent transcription factor ATF-4, CREB2, Cyclic AMP-responsive element-binding protein 2, Tax-responsive enhancer element-binding protein 67
| 产品类型 | Monoclonal |
| 基因名称 | activating transcription factor 4 (tax-responsive enhancer element B67) |
| 经测试应用 | WB, IHC |
| 宿主 | Rabbit |
| 种属反应性 | Human, Mouse |
| 免疫原 | A synthesized peptide derived from human ATF4 |
| 理论分子量 | 39 kDa |
| 实际分子量 | 45-55 kDa |
| Gene ID(NCBI) | 468 |
| GeneBank Accession Number | BC022088 |
| UNIPROT | P18848 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:2500-1:25000 |
| 背景信息 | This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. |
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