| 别名 | 240769G5, EC:2.7.11.1, NF kappa B activating kinase, NF-kappa-B-activating kinase, Serine/threonine protein kinase TBK1 |
| 产品类型 | Monoclonal |
| 基因名称 | TANK-binding kinase 1 |
| 经测试应用 | WB, IHC, IF/ICC |
| 宿主 | Rabbit |
| 种属反应性 | Human, Mouse, Rat |
| 免疫原 | A synthesized peptide derived from human TBK1 |
| 理论分子量 | 84 kDa |
| 实际分子量 | 75-85 kDa |
| Gene ID(NCBI) | 29110 |
| GeneBank Accession Number | BC034950 |
| UNIPROT | Q9UHD2 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:500-1:4000 |
| 背景信息 | The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. The protein is also an important kinase for antiviral innate immunity response. |