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ubiquitin Recombinant antibody

  • 货号:
    RM20174
  • 规格:
    20ul
    50ul
    100ul
  • 价格:
    0.00

产品参数

别名UBB, ubiquitin B, 6H6, Polyubiquitin B, Polyubiquitin-B
产品类型Monoclonal
基因名称ubiquitin B
经测试应用WB, IHC, IF/ICC
宿主Rabbit
种属反应性Human, Mouse, Rat
免疫原A synthesized peptide derived from human ubiquitin
Gene ID(NCBI)7314
GeneBank Accession Number‍BC000379‍
UNIPROT‍‍‍‍‍P0CG47‍
形式Liquid
保存条件Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例1:5000-1:50000
背景信息This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants.