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Fibrillarin Polyclonal antibody

  • 货号:
    AP20230
  • 规格:
    20ul
    50ul
    100ul
  • 价格:
    0.00

产品参数

别名FBL, EC:2.1.1.-, FIB, FIB1, FLRN
产品类型Polyclonal
基因名称fibrillarin
经测试应用WB, IF/ICC
宿主Rabbit
种属反应性Human, Mouse, Rat
免疫原A synthesized peptide derived from human Fibrillarin
理论分子量34 kDa
实际分子量34 kDa
Gene ID(NCBI)2091
GeneBank Accession Number‍‍BC019260‍
UNIPROTP22087
形式Liquid
保存条件Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例1:500-1:3000
背景信息This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.