| 别名 | HMG-2, HMG2, HMG 2, High mobility group protein B2, High mobility group protein 2 |
| 产品类型 | Polyclonal |
| 基因名称 | high-mobility group box 2 |
| 经测试应用 | WB, IF/ICC |
| 宿主 | Rabbit |
| 种属反应性 | Human, Mouse, Rat |
| 免疫原 | A synthesized peptide derived from human HMGB2 |
| 理论分子量 | 24 kDa |
| 实际分子量 | 20-25 kDa |
| Gene ID(NCBI) | 3148 |
| GeneBank Accession Number | BC001063 |
| UNIPROT | P26583 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:250-1:1500 |
| 背景信息 | This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. |