| 产品类型 | Polyclonal |
| 基因名称 | lipoic acid synthetase |
| 经测试应用 | WB, IHC |
| 宿主 | Rabbit |
| 种属反应性 | Human, Mouse, Rat |
| 免疫原 | A synthesized peptide derived from human LIAS |
| 理论分子量 | 42 kDa |
| 实际分子量 | 34-42 kDa |
| Gene ID(NCBI) | 11019 |
| GeneBank Accession Number | BC023635 |
| UNIPROT | O43766 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:500-1:2500 |
| 背景信息 | The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. Localized in the mitochondrion, this iron-sulfur enzyme catalyzes the final step in the de novo pathway for the biosynthesis of lipoic acid, a potent antioxidant. The deficient expression of this enzyme has been linked to conditions such as diabetes, atherosclerosis and neonatal-onset epilepsy. Alternative splicing occurs at this locus, and several transcript variants encoding distinct isoforms have been identified. |
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