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TMEM173/STING Polyclonal antibody

  • 货号:
    AP20122
  • 规格:
    20ul
    50ul
    100ul
  • 价格:
    0.00

产品参数

别名STING, Endoplasmic reticulum interferon stimulator, ERIS, MITA, MPYS
产品类型Polyclonal
基因名称transmembrane protein 173
经测试应用WB, IHC, IF/ICC, IF-P
宿主Rabbit
种属反应性Human, Mouse, Rat
免疫原A synthesized peptide derived from human TMEM173/STING
理论分子量42 kDa
实际分子量35-40 kDa
Gene ID(NCBI)340061
GeneBank Accession NumberBC047779
UNIPROTQ86WV6
形式Liquid
保存条件Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例1:1000-1:5000
背景信息This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.