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SLC7A11/xCT Polyclonal antibody

SLC7A11/xCT Polyclonal antibody

货号：
AP20121
规格：

20ul

50ul

100ul
价格：
￥0.00

产品说明书前往锐竞购买

产品参数

别名	SLC7A11, xCT, Amino acid transport system xc, Amino acid transport system xc-, CCBR1
产品类型	Polyclonal
基因名称	solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
经测试应用	WB, IHC, IP
宿主	Rabbit
种属反应性	Human
免疫原	A synthesized peptide derived from human SLC7A11/xCT
理论分子量	55 kDa
实际分子量	45-55 kDa
Gene ID(NCBI)	23657
GeneBank Accession Number	BC012087
UNIPROT	Q9UPY5
形式	Liquid
保存条件	Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例	1:500-1:2000
背景信息	This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.

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