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FAK Monoclonal antibody

  • 货号:
    AM20235
  • 规格:
    20ul
    50ul
    100ul
  • 价格:
    0.00

产品参数

别名PTK2, 2C5B9, EC:2.7.10.2, FADK 1, FAK1
产品类型Monoclonal
基因名称PTK2 protein tyrosine kinase 2
经测试应用WB, IHC, IF/ICC
宿主Mouse
种属反应性Human, Mouse, Rat
免疫原A synthesized peptide derived from human FAK
理论分子量119 kDa
实际分子量120-130 kDa
Gene ID(NCBI)5747
GeneBank Accession Number‍‍BC028733‍
UNIPROTQ05397
形式Liquid
保存条件Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例1:2500-1:25000
背景信息This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.