| 别名 | ABC43, ABCD3, PMP70, PXMP1 |
| 产品类型 | Monoclonal |
| 基因名称 | ATP-binding cassette, sub-family D (ALD), member 3 |
| 经测试应用 | WB |
| 宿主 | Mouse |
| 种属反应性 | Human |
| 免疫原 | A synthesized peptide derived from human ABCD3 |
| 理论分子量 | 72 kDa |
| 实际分子量 | 72 kDa |
| Gene ID(NCBI) | 5825 |
| GeneBank Accession Number | BC068509 |
| UNIPROT | P28288 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:500-1:1000 |
| 背景信息 | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |