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ABCD3 Monoclonal antibody

  • 货号:
    AM20215
  • 规格:
    20ul
    50ul
    100ul
  • 价格:
    0.00

产品参数

别名ABC43, ABCD3, PMP70, PXMP1
产品类型Monoclonal
基因名称ATP-binding cassette, sub-family D (ALD), member 3
经测试应用WB
宿主Mouse
种属反应性Human
免疫原A synthesized peptide derived from human ABCD3
理论分子量72 kDa
实际分子量72 kDa
Gene ID(NCBI)5825
GeneBank Accession NumberBC068509‍
UNIPROTP28288
形式Liquid
保存条件Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例1:500-1:1000
背景信息The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms.