咨询热线:

020-3107 8154

IL-2 Monoclonal antibody

  • 货号:
    AM20212
  • 规格:
    20ul
    50ul
    100ul
  • 价格:
    0.00

产品参数

别名IL2, 2F11C5, IL 2, interleukin 2, Interleukin-2
产品类型Monoclonal
基因名称interleukin 2
经测试应用WB, IHC, IF/ICC
宿主Mouse
种属反应性Human
免疫原A synthesized peptide derived from human IL-2
理论分子量18 kDa
实际分子量15 kDa
Gene ID(NCBI)3558
GeneBank Accession NumberBC070338
UNIPROTP60568
形式Liquid
保存条件Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例1:500-1:2000
背景信息This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4, IL7, IL9, IL15, IL21, erythropoietin, and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4+ and CD8+ T lymphocytes, that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2R) is a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.