| 别名 | KRAS, 4H4G7, C K RAS, c Ki ras, c-Ki-ras |
| 产品类型 | Monoclonal |
| 基因名称 | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog |
| 经测试应用 | WB, IHC, IF/ICC |
| 宿主 | Mouse |
| 种属反应性 | Human, Mouse, Rat |
| 免疫原 | A synthesized peptide derived from human KRAS |
| 理论分子量 | 21 kDa |
| 实际分子量 | 21 kDa |
| Gene ID(NCBI) | 3845 |
| GeneBank Accession Number | BC013572 |
| UNIPROT | P01116 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:10000-1:30000 |
| 背景信息 | This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. |