| 别名 | 2B5A10, APG7 LIKE, APG7L, ATG12-activating enzyme E1 ATG7, Autophagy related protein 7 |
| 产品类型 | Monoclonal |
| 基因名称 | ATG7 autophagy related 7 homolog (S. cerevisiae) |
| 经测试应用 | WB, IHC, IF/ICC |
| 宿主 | Mouse |
| 种属反应性 | Human, Mouse, Rat |
| 免疫原 | A synthesized peptide derived from human ATG7 |
| 理论分子量 | 78 kDa |
| 实际分子量 | 70-78 kDa |
| Gene ID(NCBI) | 10533 |
| GeneBank Accession Number | BC000091 |
| UNIPROT | O95352 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:2500-1:25000 |
| 背景信息 | This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. |