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Caspase 9/P35 Monoclonal antibody

  • 货号:
    AM20149
  • 规格:
    20ul
    50ul
    100ul
  • 价格:
    0.00

产品参数

别名CASP9, Caspase 9, Caspase 9/p35/p10, 1B7G2, APAF 3
产品类型Monoclonal
基因名称caspase 9, apoptosis-related cysteine peptidase
经测试应用WB, IHC, IF/ICC
宿主Mouse
种属反应性Human, Mouse
免疫原A synthesized peptide derived from human Caspase 9
理论分子量46 kDa
实际分子量42-50 kDa
Gene ID(NCBI)842
GeneBank Accession NumberBC002452‍
UNIPROTP55211‍
形式Liquid
保存条件Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例1:500-1:1000
背景信息This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.