| 别名 | CASP9, Caspase 9, Caspase 9/p35/p10, 1B7G2, APAF 3 |
| 产品类型 | Monoclonal |
| 基因名称 | caspase 9, apoptosis-related cysteine peptidase |
| 经测试应用 | WB, IHC, IF/ICC |
| 宿主 | Mouse |
| 种属反应性 | Human, Mouse |
| 免疫原 | A synthesized peptide derived from human Caspase 9 |
| 理论分子量 | 46 kDa |
| 实际分子量 | 42-50 kDa |
| Gene ID(NCBI) | 842 |
| GeneBank Accession Number | BC002452 |
| UNIPROT | P55211 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:500-1:1000 |
| 背景信息 | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. |