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P53 Monoclonal antibody

  • 货号:
    AM20115
  • 规格:
    20ul
    50ul
    100ul
  • 价格:
    0.00

产品参数

别名P53, Tumour Protein p53, Tumor suppressor p53, tumor protein p53, Antigen NY-CO-13
产品类型Monoclonal
基因名称tumor protein p53
经测试应用WB, IHC, IF/ICC
宿主Mouse
种属反应性Human,Rat
免疫原A synthesized peptide derived from human P53
理论分子量53 kDa
实际分子量53 kDa
Gene ID(NCBI)7157
GeneBank Accession NumberBC003596
UNIPROTP04637
形式Liquid
保存条件Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例1:2500-1:25000
背景信息This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).