| 别名 | IPOA, hSod1, homodimer, EC:1.15.1.1, ALS1 |
| 产品类型 | Monoclonal |
| 基因名称 | superoxide dismutase 1, soluble |
| 经测试应用 | WB, IHC, IF/ICC |
| 宿主 | Mouse |
| 种属反应性 | Human,Mouse,Rat,Pig |
| 免疫原 | A synthesized peptide derived from human SOD1 |
| 理论分子量 | 16 kDa |
| 实际分子量 | 15 kDa |
| Gene ID(NCBI) | 6647 |
| GeneBank Accession Number | BC001034 |
| UNIPROT | P00441 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:2500-1:25000 |
| 背景信息 | The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. |