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SOD1 Monoclonal antibody

  • 货号:
    AM20113
  • 规格:
    20ul
    50ul
    100ul
  • 价格:
    0.00

产品参数

别名IPOA, hSod1, homodimer, EC:1.15.1.1, ALS1
产品类型Monoclonal
基因名称superoxide dismutase 1, soluble
经测试应用WB, IHC, IF/ICC
宿主Mouse
种属反应性Human,Mouse,Rat,Pig
免疫原A synthesized peptide derived from human SOD1
理论分子量16 kDa
实际分子量15 kDa
Gene ID(NCBI)6647
GeneBank Accession NumberBC001034
UNIPROTP00441
形式Liquid
保存条件Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例1:2500-1:25000
背景信息The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.