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E-cadherin Monoclonal antibody

E-cadherin Monoclonal antibody

货号：
AM20111
规格：

20ul

50ul

100ul
价格：
￥0.00

产品说明书前往锐竞购买

产品参数

别名	Arc 1; Cadherin 1; CD324; CDH1; CDHE; E cadherin; ECAD; E-cad; E-cadherin
产品类型	Monoclonal
基因名称	cadherin 1, type 1, E-cadherin (epithelial)
经测试应用	WB, IF, IHC
宿主	Mouse
种属反应性	Human, Rat
免疫原	A synthesized peptide derived from human E-cadherin
理论分子量	97 kDa
实际分子量	120 kDa
Gene ID(NCBI)	999
GeneBank Accession Number	BC141838
UNIPROT	P12830
形式	Liquid
保存条件	Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例	1:1000-1:5000
背景信息	This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16.

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