Caspase 3 Mouse Monoclonal antibody
CASP3, Caspase3, Caspase 3, CASP-3, CASP 3
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货号:
AM20103 -
规格:
- 20ul
- 50ul
- 100ul
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价格:
¥0.00
| 产品类型 | Monoclonal |
| 基因名称 | caspase 3, apoptosis-related cysteine peptidase |
| 经测试应用 | WB, IHC, IF/ICC |
| 宿主 | Mouse |
| 种属反应性 | Human, Mouse |
| 免疫原 | A synthesized peptide derived from human Caspase 3 |
| 理论分子量 | 32 kDa |
| 实际分子量 | 17 kDa |
| Gene ID(NCBI) | 836 |
| GeneBank Accession Number | BC016926 |
| UNIPROT | P42574 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:1000-1:3000 |
| 背景信息 | The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. |