Lamin A/C Rabbit Monoclonal antibody
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货号：
RM20186 -
规格：
- 50ul
- 100ul
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价格：
￥0.00
产品参数
| 别名 | LaminA/C, 5I16, lamin A, Lamin-A/C, LMN1 |
| 产品类型 | 内参抗体 |
| 基因名称 | lamin A/C |
| 经测试应用 | WB, IHC, IF/ICC |
| 宿主 | Rabbit |
| 种属反应性 | Human, Mouse, Rat |
| 免疫原 | A synthesized peptide derived from human Lamin A/C |
| 克隆类型 | Recombinant |
| 理论分子量 | 65 kDa |
| 实际分子量 | 60-70 kDa |
| Gene ID(NCBI) | 4000 |
| GeneBank Accession Number | BC003162 |
| UNIPROT | P02545 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:10000-1:50000 |
| 背景信息 | The protein encoded by this gene is part of the nuclear lamina, a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. |
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