| 别名 | VCL, MVCL, MV, Metavinculin, CMD1W |
| 产品类型 | 内参抗体 |
| 基因名称 | vinculin |
| 经测试应用 | WB, IHC, IF/ICC |
| 宿主 | Mouse |
| 种属反应性 | Human, Mouse, Rat, Pig |
| 免疫原 | A synthesized peptide derived from human Vinculin |
| 克隆类型 | Monoclonal |
| 理论分子量 | 124 kDa |
| 实际分子量 | 124 kDa |
| Gene ID(NCBI) | 7414 |
| GeneBank Accession Number | BC039174 |
| UNIPROT | P18206 |
| 形式 | Liquid |
| 保存条件 | Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage. |
| 推荐稀释比例 | 1:2500-1:25000 |
| 背景信息 | Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. |