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GAPDH Mouse Monoclonal antibody

  • 货号:
    AM20101
  • 规格:
    50ul
    100ul
  • 价格:
    0.00

产品参数

别名G3PD, GAPD, GAPDH, OK/SW cl.12
产品类型内参抗体
基因名称glyceraldehyde-3-phosphate dehydrogenase
经测试应用WB, IF/ICC
宿主Mouse
种属反应性Human, Mouse, Rat, Pig
免疫原A synthesized peptide derived from human GAPDH
克隆类型Monoclonal
理论分子量36 kDa
实际分子量36 kDa
Gene ID(NCBI)2597
GeneBank Accession NumberBC004109
UNIPROTP04406
形式Liquid
保存条件Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20℃ storage.
推荐稀释比例1:25000-1:250000
背景信息This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants.
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