DDD107498
DDD107498 (M-5717, DDD-498) 是一种 P. falciparum translation elongation factor 2 的抑制剂。DDD107498 具有针对疟原虫寄生虫的多个生命周期阶段的有效地抗疟疾的活性。
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货号:
TK0468 -
规格:
- 5mg
-
价格:
¥0.00
DDD107498 (M-5717, DDD-498) 是一种 P. falciparum translation elongation factor 2 的抑制剂。DDD107498 具有针对疟原虫寄生虫的多个生命周期阶段的有效地抗疟疾的活性。
| CAS No. | 1469439-69-7 |
| 生物活性 | DDD107498 (DDD-498) is a potent and orally active antimalarial agent, inhibits multiple life-cycle stages of the parasite, with an EC50 of 1 nM against P. falciparum 3D7. DDD107498 inhibits protein synthesis by targeting eEF2/CaMKIII, with an EC50 of 2 nM for WT-PfeEF2. |
| 分子式 | C27H31FN4O2 |
| 分子量 | 462.56 |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存条件 | 4°C, protect from light,*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| 溶解性数据 | DMSO : 100 mg/mL (216.19 mM; Need ultrasonic) |
| 纯度及产品资料 | 98% |