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DDD107498

DDD107498 (M-5717, DDD-498) 是一种 P. falciparum translation elongation factor 2 的抑制剂。DDD107498 具有针对疟原虫寄生虫的多个生命周期阶段的有效地抗疟疾的活性。

  • 货号:
    TK0468
  • 规格:
    5mg
  • 价格:
    0.00

产品参数

CAS No.1469439-69-7
生物活性DDD107498 (DDD-498) is a potent and orally active antimalarial agent, inhibits multiple life-cycle stages of the parasite, with an EC50 of 1 nM against P. falciparum 3D7. DDD107498 inhibits protein synthesis by targeting eEF2/CaMKIII, with an EC50 of 2 nM for WT-PfeEF2.
分子式C27H31FN4O2
分子量462.56
运输条件Room temperature in continental US; may vary elsewhere.
储存条件4°C, protect from light,*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶解性数据DMSO : 100 mg/mL (216.19 mM; Need ultrasonic)
纯度及产品资料98%