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Trolox

Trolox is a cell-permeable, water-soluble derivative of vitamin E with potent antioxidant properties.

货号：
TK0348
规格：

100mg

500mg

1g
价格：
￥0.00

产品参数

CAS No.	53188-07-1
生物活性	Trolox is an analogue of vitamin E with a powerful antioxidant effect. Trolox is also a powerful inhibitor of membrane damage.
分子式	C14H18O4
分子量	250.29
运输条件	Room temperature in continental US; may vary elsewhere.
储存条件	Powder -20°C 3 years
溶解性数据	DMSO : ≥ 100 mg/mL (399.54 mM)
体外研究	Trolox has shown to protect mammalian cells from oxidative damage. Trolox is effective in preventing myocyte necrosis in cell culture studies and in a canine model of two hours of left anterior descending coronary artery (LAD) occlusion followed by four hours of reperfusion. Trolox could prevent oxidative stress-induced apoptosis in thymocytes. Pre- or posttreatment of cells with Trolox reduced H2O2-induced DNA fragmentation to control levels and below. . Trolox is a hydrophilic analogue of alpha-tocopherol and reported to scavenge peroxyl radicals better than vitamin E in sodium dodecyl sulfate micelles and in liposomes. Trolox prolongs substantially the survival of human ventricular myocytes and hepatocyte against oxyradicals generated with xanthine oxidase plus hypoxanthine, and prevented lysis of red cells exposed to an azo-initiator.
文献	•Cell Death Dis. 2021 Apr 1;12(4):338. •Oxid Med Cell Longev. 2020 Jan 27;2020:5829521. •Neurotox Res. 2020 Dec;38(4):859-870.
纯度及产品资料	98%

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