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抑制剂/激活剂

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凋亡与自噬

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Z-YVAD-FMK

Z-YVAD-FMK 是一种具有抗炎和抗肿瘤活性的细胞渗透性的、不可逆的 caspase-1 特异性抑制剂。

货号：
TK0182
规格：

1mg
价格：
￥0.00

产品参数

CAS No.	210344-97-1
生物活性	Z-YVAD-FMK is a cell-permeable caspase-1 and -4 inhibitor with anti-inflammatory and anti-tumor activities.
分子式	C31H39N4O9F
分子量	630.66
运输条件	Room temperature in continental US; may vary elsewhere.
储存条件	Powder -20℃ 3 years
溶解性数据	DMSO : 125 mg/mL (198.21 mM; Need ultrasonic)
体外研究	Z-YVAD-FMK (100 μM; 24 hours) significantly downregulated the growth inhibition induced by butyrate in Caco-2 cells. Z-YVAD-FMK (20 μM; pre 1 hour; 24 hours) attenuates the apoptotic induction of III-10 on both HepG2 and BEL-7402 cells, the apoptotic rate of -10 on HepG2 cells is reduced by Z-VAD-FMK from 19.88% to 8.34%, while that on BEL-7402 cells is reduced from 17.56% to 11.98%.
文献	暂无相关参考文献
纯度及产品资料	≥98%

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